Recombinant Mouse KLRD1 protein

Description

Recombinant protein of human killer cell lectin receptor subfamily D, member 1 (KLRD1), transcription variant 1

Species: Human

Expression host: HEK293T

An expression cDNA clone or a AA sequence:

The recombinant protein was produced with the TrueORF clone, RC206991. Click on the TrueORF clone link to view the cDNA and protein sequences.

Label: C-Myc / DDK

MW predicted: 20.3 kDa

Concentration:

> 50 ugs / mL as determined by the BCA microplate method

Purity:

> 80% as determined by SDS-PAGE and Coomassie blue staining

Buffer:

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Preparation:

The recombinant protein was captured through an anti-DDK affinity column followed by conventional chromatography steps.

Storage: Store at -80 ° C.

Stability

Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

RefSeq: NP_002253

Locus ID: 3824

UniProt ID: Q13241, Q53ZY6

Cytogenetics: 12p13.2

Refseq Size: 3258

Refseq ORF: 537

Synonyms: CD94

Summary

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen that is preferentially expressed on NK cells and is classified as a type II membrane protein because it has an outer C-terminal. Several transcription variants have been found that encode different isoforms for this gene. [provided by RefSeq, May 2017]

Protein families: Transmembrane

Protein pathways

Antigen processing and presentation, graft versus host disease, natural killer cell-mediated cytotoxicity

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